Sulfamoyl Heteroarylcarboxylic Acids as Promising Metallo-β-Lactamase Inhibitors for Controlling Bacterial Carbapenem Resistance
ABSTRACT Production of metallo-β-lactamases (MBLs), which hydrolyze carbapenems, is a cause of carbapenem resistance in Enterobacteriaceae. Development of effective inhibitors for MBLs is one approach to restore carbapenem efficacy in carbapenem-resistant Enterobacteriaceae (CRE). We report here tha...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Subjects: | |
Online Access: | https://doaj.org/article/06c7870989aa4b839f1bdca139f23749 |
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