Sulfamoyl Heteroarylcarboxylic Acids as Promising Metallo-β-Lactamase Inhibitors for Controlling Bacterial Carbapenem Resistance
ABSTRACT Production of metallo-β-lactamases (MBLs), which hydrolyze carbapenems, is a cause of carbapenem resistance in Enterobacteriaceae. Development of effective inhibitors for MBLs is one approach to restore carbapenem efficacy in carbapenem-resistant Enterobacteriaceae (CRE). We report here tha...
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Autores principales: | Jun-ichi Wachino, Wanchun Jin, Kouji Kimura, Hiromasa Kurosaki, Ayato Sato, Yoshichika Arakawa |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/06c7870989aa4b839f1bdca139f23749 |
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