Thioflavin T fluoresces as excimer in highly concentrated aqueous solutions and as monomer being incorporated in amyloid fibrils

Abstract Fluorescence of thioflavin T (ThT) is a proven tool for amyloid fibrils study. The correct model of ThT binding to fibrils is crucial to clarify amyloid fibrils structure and mechanism of their formation. Although there are convincing evidences that ThT has molecular rotor nature, implying...

Full description

Saved in:
Bibliographic Details
Main Authors: Anna I. Sulatskaya, Andrey V. Lavysh, Alexander A. Maskevich, Irina M. Kuznetsova, Konstantin K. Turoverov
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/06f32f88a9e24f93b7d6feefa91a0255
Tags: Add Tag
No Tags, Be the first to tag this record!