Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish.

The ubiquitin-proteasome system plays important roles in various biological processes as it degrades the majority of cellular proteins. Adequate proteasomal degradation of crucial transcription regulators ensures the proper development of neutrophils. The ubiquitin E3 ligase of Growth factor indepen...

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Auteurs principaux: Shuo Gao, Zixuan Wang, Luxiang Wang, Haihong Wang, Hao Yuan, Xiaohui Liu, Saijuan Chen, Zhu Chen, Hugues de Thé, Wenqing Zhang, Yiyue Zhang, Jun Zhu, Jun Zhou
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/074e248f45494816a93de01799d651a8
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