A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication

Immune system participates in the development of high blood pressure. Here the authors show that cholinergic-sympathetic pathway mediated by the α7nAChR receptor and the activation of splenic T cells prime immunity during hypertension and that selective splenic denervation protects against the onset...

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Main Authors: Daniela Carnevale, Marialuisa Perrotta, Fabio Pallante, Valentina Fardella, Roberta Iacobucci, Stefania Fardella, Lorenzo Carnevale, Raimondo Carnevale, Massimiliano De Lucia, Giuseppe Cifelli, Giuseppe Lembo
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/07720ecca2404dfe8b4fc0ece093e54a
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