Metaxins are core components of mitochondrial transport adaptor complexes

Mitochondrial trafficking is carefully regulated and functionally important in neurons. Here, the authors screen C. elegans for abnormal mitochondrial distribution and identify metaxin-1 and -2, which bind Miro and microtubule motor proteins to promote mitochondrial trafficking.

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Autores principales: Yinsuo Zhao, Eli Song, Wenjuan Wang, Chung-Han Hsieh, Xinnan Wang, Wei Feng, Xiangming Wang, Kang Shen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0783f54a8c0745b8bb0ac55817195541
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