Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines.

<h4>Background</h4>We have recently shown that deregulation PI3-kinase/AKT survival pathway plays an important role in pathogenesis of diffuse large B cell lymphoma (DLBCL). In an attempt to identify newer therapeutic agents, we investigated the role of Resveratrol (trans-3,4', 5-tr...

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Autores principales: Azhar R Hussain, Shahab Uddin, Rong Bu, Omar S Khan, Saeeda O Ahmed, Maqbool Ahmed, Khawla S Al-Kuraya
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/07d26e01214c4ad9a8c821ce8c34d555
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