Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment

Abstract Background High glucose (HG) is linked to dopaminergic neuron loss and related Parkinson’s disease (PD), but the mechanism is unclear. Results Rats and differentiated SH-SY5Y cells were used to investigate the effect of HG on dopaminergic neuronal apoptotic death. We found that a 40-day HG...

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Autores principales: Changhong Tan, Xi Liu, Xiaoshuai Zhang, Wuxue Peng, Hui Wang, Wen Zhou, Jin Jiang, Lijuan Mo, Yangmei Chen, Lifen Chen
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Fyn
Acceso en línea:https://doaj.org/article/07db3d4d479a4271b34493c9b0bb7ad8
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