A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation.

Integrin signaling regulates cell migration and plays a pivotal role in developmental processes and cancer metastasis. Integrin signaling has been studied extensively and much data is available on pathway components and interactions. Yet the data is fragmented and an integrated model is missing. We...

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Autores principales: Florian Geier, Georgios Fengos, Dagmar Iber
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/07ea5036eed542188cd170c6139b6350
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