The Molecular Mechanisms of Allosteric Mutations Impairing MepR Repressor Function in Multidrug-Resistant Strains of <named-content content-type="genus-species">Staphylococcus aureus</named-content>
ABSTRACT Overexpression of the Staphylococcus aureus multidrug efflux pump MepA confers resistance to a wide variety of antimicrobials. mepA expression is controlled by MarR family member MepR, which represses mepA and autorepresses its own production. Mutations in mepR are a primary cause of mepA o...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2013
|
| Subjects: | |
| Online Access: | https://doaj.org/article/07f73ecbe7c84e91b1c2658cca5f9fe4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|