Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load.

Molecular mechanisms leading to pressure ulcer development are scarce in spite of high mortality of patients. Development of pressure ulcers that is initially observed as deep tissue injury is multifactorial. We postulate that biomechanical forces and inflammasome activation, together with ischemia...

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Autores principales: Olivera Stojadinovic, Julia Minkiewicz, Andrew Sawaya, Jonathan W Bourne, Peter Torzilli, Juan Pablo de Rivero Vaccari, W Dalton Dietrich, Robert W Keane, Marjana Tomic-Canic
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/080f8f4474f94f69a578cd5543efdf59
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