WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes

After autophagic cargo degradation, autolysosomes undergo a reformation process to recycle lysosomal membrane components. Here, Dai et al. demonstrate that the actin nucleation promoting factor WHAMM is required for autolysosome reformation by providing an actin scaffold to drive tubulation.

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Detalles Bibliográficos
Autores principales: Anbang Dai, Li Yu, Hong-Wei Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/081945393053411d8f5e25f9f81b3e8d
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