WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes

After autophagic cargo degradation, autolysosomes undergo a reformation process to recycle lysosomal membrane components. Here, Dai et al. demonstrate that the actin nucleation promoting factor WHAMM is required for autolysosome reformation by providing an actin scaffold to drive tubulation.

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Detalles Bibliográficos
Autores principales:	Anbang Dai, Li Yu, Hong-Wei Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/081945393053411d8f5e25f9f81b3e8d
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spelling	oai:doaj.org-article:081945393053411d8f5e25f9f81b3e8d2021-12-02T16:57:24ZWHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes10.1038/s41467-019-11694-92041-1723https://doaj.org/article/081945393053411d8f5e25f9f81b3e8d2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11694-9https://doaj.org/toc/2041-1723After autophagic cargo degradation, autolysosomes undergo a reformation process to recycle lysosomal membrane components. Here, Dai et al. demonstrate that the actin nucleation promoting factor WHAMM is required for autolysosome reformation by providing an actin scaffold to drive tubulation.Anbang DaiLi YuHong-Wei WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anbang Dai Li Yu Hong-Wei Wang WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
description	After autophagic cargo degradation, autolysosomes undergo a reformation process to recycle lysosomal membrane components. Here, Dai et al. demonstrate that the actin nucleation promoting factor WHAMM is required for autolysosome reformation by providing an actin scaffold to drive tubulation.
format	article
author	Anbang Dai Li Yu Hong-Wei Wang
author_facet	Anbang Dai Li Yu Hong-Wei Wang
author_sort	Anbang Dai
title	WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
title_short	WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
title_full	WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
title_fullStr	WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
title_full_unstemmed	WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
title_sort	whamm initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/081945393053411d8f5e25f9f81b3e8d
work_keys_str_mv	AT anbangdai whamminitiatesautolysosometubulationbypromotingactinpolymerizationonautolysosomes AT liyu whamminitiatesautolysosometubulationbypromotingactinpolymerizationonautolysosomes AT hongweiwang whamminitiatesautolysosometubulationbypromotingactinpolymerizationonautolysosomes
_version_	1718382545755701248

WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes

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