Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression

Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression

Abstract Fatty liver has lower tolerance against ischemia-reperfusion (I/R) injury in liver operations, including liver transplantation. Seeking to ameliorate liver injury following I/R in fatty liver, we examined the protective effect of hydrogen (H2) saline on I/R liver injury in a methionine and...

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Autores principales: Shaowei Li, Masayuki Fujino, Naotsugu Ichimaru, Ryosuke Kurokawa, Shinichi Hirano, Lisha Mou, Shiro Takahara, Terumi Takahara, Xiao-Kang Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Sirtuins
SIRT1 Expression
Molecular Hydrogen
Hepatocyte Apoptosis
Primary Hepatocytes
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0841c4ba49174275880b40a7d8379538
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https://doaj.org/article/0841c4ba49174275880b40a7d8379538

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