Synthesis and Evaluation of a Fluorine-18 Radioligand for Imaging Huntingtin Aggregates by Positron Emission Tomographic Imaging

Mutations in the huntingtin gene (HTT) triggers aggregation of huntingtin protein (mHTT), which is the hallmark pathology of neurodegenerative Huntington’s disease (HD). Development of a high affinity 18F radiotracer would enable the study of Huntington’s disease pathology using a non-invasive imagi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tanpreet Kaur, Allen F. Brooks, Alex Lapsys, Timothy J. Desmond, Jenelle Stauff, Janna Arteaga, Wade P. Winton, Peter J. H. Scott
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://doaj.org/article/0846a1b2ce224b169bddbc9d2e69f731
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!