Spiegelzymes® mirror-image hammerhead ribozymes and mirror-image DNAzymes, an alternative to siRNAs and microRNAs to cleave mRNAs in vivo?

With the discovery of small non-coding RNA (ncRNA) molecules as regulators for cellular processes, it became intriguing to develop technologies by which these regulators can be applied in molecular biology and molecular medicine. The application of ncRNAs has significantly increased our knowledge ab...

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Autores principales: Eliza Wyszko, Florian Mueller, Marta Gabryelska, Angelika Bondzio, Mariusz Popenda, Jan Barciszewski, Volker A Erdmann
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/0858e4d9f22e44b18b13cc971bf4ee70
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