Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples

Abstract Mucus hypersecretion contributes to lung function impairment observed in COPD (chronic obstructive pulmonary disease), a tobacco smoking-related disease. A detailed mucus hypersecretion adverse outcome pathway (AOP) has been constructed from literature reviews, experimental and clinical dat...

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Autores principales: Emmanuel Minet, Linsey E. Haswell, Sarah Corke, Anisha Banerjee, Andrew Baxter, Ivan Verrastro, Francisco De Abreu e Lima, Tomasz Jaunky, Simone Santopietro, Damien Breheny, Marianna D. Gaça
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/085c7701b32246ae85c6953e73f896e5
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