Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing

Adaptive immunity from both B and T cells critically controls the rejection or survival of transplanted organs. Here the authors show, by analyzing human B cell receptor repertoire in longitudinal studies of patients receiving kidney transplants, that repertoire diversity is positively associated wi...

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Autores principales:	Silvia Pineda, Tara K. Sigdel, Juliane M. Liberto, Flavio Vincenti, Marina Sirota, Minnie M. Sarwal
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/08b11559921a47c3bbc1810bb121763c
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spelling	oai:doaj.org-article:08b11559921a47c3bbc1810bb121763c2021-12-02T14:39:37ZCharacterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing10.1038/s41467-019-09930-32041-1723https://doaj.org/article/08b11559921a47c3bbc1810bb121763c2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09930-3https://doaj.org/toc/2041-1723Adaptive immunity from both B and T cells critically controls the rejection or survival of transplanted organs. Here the authors show, by analyzing human B cell receptor repertoire in longitudinal studies of patients receiving kidney transplants, that repertoire diversity is positively associated with the incidence of kidney rejection.Silvia PinedaTara K. SigdelJuliane M. LibertoFlavio VincentiMarina SirotaMinnie M. SarwalNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Silvia Pineda Tara K. Sigdel Juliane M. Liberto Flavio Vincenti Marina Sirota Minnie M. Sarwal Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
description	Adaptive immunity from both B and T cells critically controls the rejection or survival of transplanted organs. Here the authors show, by analyzing human B cell receptor repertoire in longitudinal studies of patients receiving kidney transplants, that repertoire diversity is positively associated with the incidence of kidney rejection.
format	article
author	Silvia Pineda Tara K. Sigdel Juliane M. Liberto Flavio Vincenti Marina Sirota Minnie M. Sarwal
author_facet	Silvia Pineda Tara K. Sigdel Juliane M. Liberto Flavio Vincenti Marina Sirota Minnie M. Sarwal
author_sort	Silvia Pineda
title	Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
title_short	Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
title_full	Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
title_fullStr	Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
title_full_unstemmed	Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
title_sort	characterizing pre-transplant and post-transplant kidney rejection risk by b cell immune repertoire sequencing
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/08b11559921a47c3bbc1810bb121763c
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Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing

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