A ligand-independent integrin β1 mechanosensory complex guides spindle orientation

During cell division, the orientation of the mitotic spindle is sensitive to forces exerted on the cell cortex. Here Petridou and Skourides show that such cues are sensed by a mechanosensory complex established on force activated integrin β1 independent of ligand binding.

Guardado en:
Detalles Bibliográficos
Autores principales: Nicoletta I. Petridou, Paris A. Skourides
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/08c31188016642ab98f554081dcd7e8b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!