Molecular Analysis of Elements of Melanoma Insensitivity to TCR-Engineered Adoptive Cell Therapy

Metastatic melanoma accounts for the highest number of skin cancer-related deaths. Traditional treatments are ineffective due to their inability to induce tumor regression at a high rate. Newer treatments such as immune checkpoint inhibitors (ICI), targeted therapy (BRAFi and MEKi), and T cell recep...

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Bibliographic Details
Main Author: Ali R. Jazirehi
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/08d8d2464a0546888f21b6f041850536
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