MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers.

MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers.

MicroRNAs are key regulators of gene expression and have been shown to have altered expression in a variety of cancer types, including epithelial ovarian cancer. MiRNA function is most often achieved through binding to the 3'-untranslated region of the target protein coding gene. Mutation scree...

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Bibliographic Details
Main Authors: Georgina L Ryland, Jennifer L Bearfoot, Maria A Doyle, Samantha E Boyle, David Y H Choong, Simone M Rowley, Australian Ovarian Cancer Study Group, Richard W Tothill, Kylie L Gorringe, Ian G Campbell
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/08ec2f5448d14f08b23bc274d1d87f50
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