Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii.

Toxoplasma gondii is an intracellular parasite that infects a wide range of warm-blooded species. Rats vary in their susceptibility to this parasite. The Toxo1 locus conferring Toxoplasma resistance in rats was previously mapped to a region of chromosome 10 containing Nlrp1. This gene encodes an inf...

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Auteurs principaux: Kimberly M Cirelli, Gezahegn Gorfu, Musa A Hassan, Morton Printz, Devorah Crown, Stephen H Leppla, Michael E Grigg, Jeroen P J Saeij, Mahtab Moayeri
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/08ffeadd52ba4b23a88d6edb3374c793
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