Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.

The coronaviruses (CoVs) are enveloped viruses of animals and humans associated mostly with enteric and respiratory diseases, such as the severe acute respiratory syndrome and 10-20% of all common colds. A subset of CoVs uses the cell surface aminopeptidase N (APN), a membrane-bound metalloprotease,...

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Auteurs principaux: Juan Reguera, César Santiago, Gaurav Mudgal, Desiderio Ordoño, Luis Enjuanes, José M Casasnovas
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/09121afb96c04366991a2c8c63c85b2d
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