Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

Escaping aversive stimuli is essential for complex organisms, but prolonged exposure to stress leads to maladaptive learning. Stress alters neuronal activity and neuromodulatory signaling in distributed networks, modifying behavior. Here, we describe changes in dopaminergic neuron activity and signa...

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Autores principales: Mingzheng Wu, Samuel Minkowicz, Vasin Dumrongprechachan, Pauline Hamilton, Lei Xiao, Yevgenia Kozorovitskiy
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
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Acceso en línea:https://doaj.org/article/09407d483e4f4aacbb9ca3606361d869
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