Spindle tubulin and MTOC asymmetries may explain meiotic drive in oocytes

During ‘meiotic drive’, some chromosomes can bias their spindle orientation and thus be retained in the egg. Here, the authors find that this phenomenon can be driven by microtubule force asymmetry on chromosomes with differently sized centromeres and kinetochores.

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Bibliographic Details
Main Authors: Tianyu Wu, Simon I. R. Lane, Stephanie L. Morgan, Keith T. Jones
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
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Online Access:https://doaj.org/article/0953c7263e2847f793b9899690e89c1c
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