ABCC6 deficiency promotes dyslipidemia and atherosclerosis

ABCC6 deficiency promotes dyslipidemia and atherosclerosis

Abstract ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using Ldlr −/− mice and pseudoxanthoma elasticum (PXE) patients. Mice lacking the Abcc6...

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Main Authors: Christopher Brampton, Viola Pomozi, Li-Hsieh Chen, Ailea Apana, Sara McCurdy, Janna Zoll, William A. Boisvert, Gilles Lambert, Daniel Henrion, Simon Blanchard, Sheree Kuo, Georges Leftheriotis, Ludovic Martin, Olivier Le Saux
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/095f67c8ae604bf686f99d9c7ce0ab63
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https://doaj.org/article/095f67c8ae604bf686f99d9c7ce0ab63

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