Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes

S1PR3 is a G protein coupled receptor, that has a role in inflammation. Here the authors show that in the CNS, S1PR3 may contribute to resilience to stressful experiences; resilient rodents show elevated S1pr3, and knockdown results in greater susceptibility to stress.

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Autores principales: Brian F. Corbett, Sandra Luz, Jay Arner, Jiah Pearson-Leary, Abhishek Sengupta, Deanne Taylor, Philip Gehrman, Richard Ross, Seema Bhatnagar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/0978149c6d7f469291e266b810704065
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