Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes

S1PR3 is a G protein coupled receptor, that has a role in inflammation. Here the authors show that in the CNS, S1PR3 may contribute to resilience to stressful experiences; resilient rodents show elevated S1pr3, and knockdown results in greater susceptibility to stress.

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Autores principales:	Brian F. Corbett, Sandra Luz, Jay Arner, Jiah Pearson-Leary, Abhishek Sengupta, Deanne Taylor, Philip Gehrman, Richard Ross, Seema Bhatnagar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0978149c6d7f469291e266b810704065
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spelling	oai:doaj.org-article:0978149c6d7f469291e266b8107040652021-12-02T16:58:24ZSphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes10.1038/s41467-019-10904-82041-1723https://doaj.org/article/0978149c6d7f469291e266b8107040652019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10904-8https://doaj.org/toc/2041-1723S1PR3 is a G protein coupled receptor, that has a role in inflammation. Here the authors show that in the CNS, S1PR3 may contribute to resilience to stressful experiences; resilient rodents show elevated S1pr3, and knockdown results in greater susceptibility to stress.Brian F. CorbettSandra LuzJay ArnerJiah Pearson-LearyAbhishek SenguptaDeanne TaylorPhilip GehrmanRichard RossSeema BhatnagarNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brian F. Corbett Sandra Luz Jay Arner Jiah Pearson-Leary Abhishek Sengupta Deanne Taylor Philip Gehrman Richard Ross Seema Bhatnagar Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
description	S1PR3 is a G protein coupled receptor, that has a role in inflammation. Here the authors show that in the CNS, S1PR3 may contribute to resilience to stressful experiences; resilient rodents show elevated S1pr3, and knockdown results in greater susceptibility to stress.
format	article
author	Brian F. Corbett Sandra Luz Jay Arner Jiah Pearson-Leary Abhishek Sengupta Deanne Taylor Philip Gehrman Richard Ross Seema Bhatnagar
author_facet	Brian F. Corbett Sandra Luz Jay Arner Jiah Pearson-Leary Abhishek Sengupta Deanne Taylor Philip Gehrman Richard Ross Seema Bhatnagar
author_sort	Brian F. Corbett
title	Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
title_short	Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
title_full	Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
title_fullStr	Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
title_full_unstemmed	Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
title_sort	sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0978149c6d7f469291e266b810704065
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Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes

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