miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster

miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster

Anaplastic thyroid cancer (ATC) is an aggressive, highly metastatic cancer that expresses high levels of the microRNA (miR)-17-92 cluster. We employ an miR inhibitor system to study the function of the different miRs within the miR-17-92 cluster based on seed sequence homology in the ATC SW579 cell...

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Detalles Bibliográficos
Autores principales: Yan Sweat, Ryan J. Ries, Mason Sweat, Dan Su, Fan Shao, Steven Eliason, Brad A. Amendt
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
miR-17
plasmid-based microRNA inhibitor system (PMIS)
thyroid cancer
miR-17-92 cluster
miR mouse model
miR-17 tumor suppressor
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/098fbd2b208b4b2cb254042c56488a4d
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https://doaj.org/article/098fbd2b208b4b2cb254042c56488a4d

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