Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling
Recent reports suggest the spatial and temporal coupling of receptor-effector interactions, with the potential to diversify downstream responses. Here authors demonstrate the temporal coupling of cognate and non-cognate G protein interactions through priming of GPCR conformation.
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Autores principales: | Tejas M. Gupte, Michael Ritt, Matthew Dysthe, Rabia U. Malik, Sivaraj Sivaramakrishnan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/09a540a2a875492bb09d5e57994f67b2 |
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