Reconstructing and counting genomic fragments through tagmentation-based haploid phasing

Abstract Single-cell sequencing provides a new level of granularity in studying the heterogeneous nature of cancer cells. For some cancers, this heterogeneity is the result of copy number changes of genes within the cellular genomes. The ability to accurately determine such copy number changes is cr...

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Autores principales: Patrick P. T. Leong, Aleksandar Mihajlović, Nadežda Bogdanović, Luka Breberina, Larry Xi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/09b5a697e27d46549e20b82bd83e072f
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