Reconstructing and counting genomic fragments through tagmentation-based haploid phasing
Abstract Single-cell sequencing provides a new level of granularity in studying the heterogeneous nature of cancer cells. For some cancers, this heterogeneity is the result of copy number changes of genes within the cellular genomes. The ability to accurately determine such copy number changes is cr...
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Main Authors: | Patrick P. T. Leong, Aleksandar Mihajlović, Nadežda Bogdanović, Luka Breberina, Larry Xi |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/09b5a697e27d46549e20b82bd83e072f |
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