Reconstructing and counting genomic fragments through tagmentation-based haploid phasing

Abstract Single-cell sequencing provides a new level of granularity in studying the heterogeneous nature of cancer cells. For some cancers, this heterogeneity is the result of copy number changes of genes within the cellular genomes. The ability to accurately determine such copy number changes is cr...

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Auteurs principaux: Patrick P. T. Leong, Aleksandar Mihajlović, Nadežda Bogdanović, Luka Breberina, Larry Xi
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/09b5a697e27d46549e20b82bd83e072f
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