ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

Different roles of specific RNA-related factors in DNA repair have now been reported. Here the authors reveal a role for RNA-editing by ADAR in DNA end resection following double strand break formation and a change in pattern of ADAR2-mediated A-to-I editing.

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Bibliographic Details
Main Authors: Sonia Jimeno, Rosario Prados-Carvajal, María Jesús Fernández-Ávila, Sonia Silva, Domenico Alessandro Silvestris, Martín Endara-Coll, Guillermo Rodríguez-Real, Judit Domingo-Prim, Fernando Mejías-Navarro, Amador Romero-Franco, Silvia Jimeno-González, Sonia Barroso, Valeriana Cesarini, Andrés Aguilera, Angela Gallo, Neus Visa, Pablo Huertas
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
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Online Access:https://doaj.org/article/09d9d77f3a254b6e952ffa2219df630e
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https://doaj.org/article/09d9d77f3a254b6e952ffa2219df630e

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