Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts
The role of O-glycosylation in the malaria life cycle is largely unknown. Here, the authors identify a Plasmodium protein O-fucosyltransferase and show that it is important for normal trafficking of a subset of surface proteins, particularly CSP and TRAP, and efficient infection of mosquito and vert...
Enregistré dans:
Auteurs principaux: | Sash Lopaticki, Annie S. P. Yang, Alan John, Nichollas E. Scott, James P. Lingford, Matthew T. O’Neill, Sara M. Erickson, Nicole C. McKenzie, Charlie Jennison, Lachlan W. Whitehead, Donna N. Douglas, Norman M. Kneteman, Ethan D. Goddard-Borger, Justin A. Boddey |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/09e0a0fb76224df8a67b76f39e4a21ef |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Trefoil factors share a lectin activity that defines their role in mucus
par: Michael A. Järvå, et autres
Publié: (2020) -
Fluorinated rhamnosides inhibit cellular fucosylation
par: Johan F. A. Pijnenborg, et autres
Publié: (2021) -
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.
par: Brad E Sleebs, et autres
Publié: (2014) -
Ancient origin of fucosylated xyloglucan in charophycean green algae
par: Maria Dalgaard Mikkelsen, et autres
Publié: (2021) -
The possible association of clusterin fucosylation changes with male fertility disorders
par: Ewa Janiszewska, et autres
Publié: (2021)