Human Cytomegalovirus Genomes Survive Mitosis via the IE19 Chromatin-Tethering Domain

ABSTRACT The genomes of DNA tumor viruses regain nuclear localization after nuclear envelope breakdown during mitosis through the action of a viral protein with a chromatin-tethering domain (CTD). Here, we report that the human cytomegalovirus (HCMV) genome is maintained during mitosis by the CTD of...

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Auteurs principaux: Shelby M. Lyon, Kristen D. Yetming, Christina Paulus, Michael Nevels, Robert F. Kalejta
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/0a07340b1ba840cd8eb8f8c1d7c83cff
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