Protein tyrosine phosphatase receptor type O (PTPRO) knockdown enhances the proliferative, invasive and angiogenic activities of trophoblast cells by suppressing ER resident protein 44 (ERp44) expression in preeclampsia

Preeclampsia (PE), a pregnancy-specific syndrome, is the primary cause of maternal mortality. This work was designed to investigate the specific functions of PTPRO/ ERp44 in the biological behaviors of trophoblast cells and elucidate the underlying molecular mechanism. Constructed siRNA-PTPRO and ER...

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Bibliographic Details
Main Authors: Yang Yang, Xiaoxia Qiu, Fang Wang
Format: article
Language:EN
Published: Taylor & Francis Group 2021
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Online Access:https://doaj.org/article/0a0e1977ffef4fe6a388b4d08d1fe197
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