The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma

Abstract The Warburg effect is a metabolic hallmark of cancer. Tumor cells rapidly adjust their energy source to glycolysis in order to efficiently proliferate in a hypoxic environment, but the mechanism underlying this switch remains incompletely understood. Here, we show that hypoxia potently indu...

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Autores principales: Fangfang Jin, Yanbo Wang, Yanan Zhu, Shan Li, Ying Liu, Cheng Chen, Xiaohua Wang, Ke Zen, Limin Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0a1c7709519d43c2ab6c9d02a8031c76
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