Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment of patrolling monocytes, which clear cancer cells a...

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Auteurs principaux: Michael P. Plebanek, Nicholas L. Angeloni, Elena Vinokour, Jia Li, Anna Henkin, Dalia Martinez-Marin, Stephanie Filleur, Reshma Bhowmick, Jack Henkin, Stephen D. Miller, Igal Ifergan, Yesung Lee, Iman Osman, C. Shad Thaxton, Olga V. Volpert
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/0a21f57d94e44252ad7ff8007fe02002
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