Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche
Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment of patrolling monocytes, which clear cancer cells a...
Guardado en:
Autores principales: | Michael P. Plebanek, Nicholas L. Angeloni, Elena Vinokour, Jia Li, Anna Henkin, Dalia Martinez-Marin, Stephanie Filleur, Reshma Bhowmick, Jack Henkin, Stephen D. Miller, Igal Ifergan, Yesung Lee, Iman Osman, C. Shad Thaxton, Olga V. Volpert |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0a21f57d94e44252ad7ff8007fe02002 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
por: Clare L. V. Westhorpe, et al.
Publicado: (2018) -
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis
por: Zhicheng Zeng, et al.
Publicado: (2018) -
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis
por: Cristina Clemente, et al.
Publicado: (2018) -
Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: their emerging role in tumor heterogeneity
por: Odessa Schillaci, et al.
Publicado: (2017) -
Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery
por: Simone Di Franco, et al.
Publicado: (2021)