Palladium-catalyzed α-arylation for the addition of small rings to aromatic compounds

Methods to prepare small, strained rings are sought after due to the importance of such scaffolds in medicinal chemistry. Here, the authors report a palladium-catalyzed α-arylation of cyclopropyl, cyclobutyl and azetidinyl esters.

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Autores principales: Zhi-Tao He, John F. Hartwig
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/0a82f86cdee2462bac4e2ef54fef7ea5
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