Palladium-catalyzed α-arylation for the addition of small rings to aromatic compounds
Methods to prepare small, strained rings are sought after due to the importance of such scaffolds in medicinal chemistry. Here, the authors report a palladium-catalyzed α-arylation of cyclopropyl, cyclobutyl and azetidinyl esters.
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| Main Authors: | Zhi-Tao He, John F. Hartwig |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/0a82f86cdee2462bac4e2ef54fef7ea5 |
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