BAX and SMAC regulate bistable properties of the apoptotic caspase system

Abstract The initiation of apoptosis is a core mechanism in cellular biology by which organisms control the removal of damaged or unnecessary cells. The irreversible activation of caspases is essential for apoptosis, and mathematical models have demonstrated that the process is tightly regulated by...

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Auteurs principaux: Stephanie McKenna, Lucía García-Gutiérrez, David Matallanas, Dirk Fey
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/0aa6015556d4479ab8ffa900097c7e38
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