Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis

The transcription factor Grhl3 is known to play a role in the nucleus during epidermal differentiation. Here, the authors report that Grhl3 is also cytoplasmic and membrane-localized, increasing mechanical stiffness by upregulating actomyosin networks.

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Autores principales: Chiharu Kimura-Yoshida, Kyoko Mochida, Masa-aki Nakaya, Takeomi Mizutani, Isao Matsuo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0aaadb922aff4943a14591e2ed41d58a
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