A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts

Yayun Liang,1 Benford Mafuvadze,1 Cynthia Besch-Williford,2 Salman M Hyder1 1Deparment of Biomedical Sciences and Dalton Cardiovascular Research Center, Columbia, MO, USA; 2IDEXX BioResearch, Columbia, MO, USA Background: Between 30 and 40% of human breast cancers express a defective tumor suppresso...

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Autores principales: Liang Y, Mafuvadze B, Besch-Williford C, Hyder SM
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2018
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p53
Acceso en línea:https://doaj.org/article/0acb0cb4cb3941b5afe2ed4d44ac85de
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