Rapid Emergence of T Follicular Helper and Germinal Center B Cells Following Antiretroviral Therapy in Advanced HIV Disease

Rapid Emergence of T Follicular Helper and Germinal Center B Cells Following Antiretroviral Therapy in Advanced HIV Disease

Low nadir CD4 T-cell counts in HIV+ patients are associated with high morbidity and mortality and lasting immune dysfunction, even after antiretroviral therapy (ART). The early events of immune recovery of T cells and B cells in severely lymphopenic HIV+ patients have not been fully characterized. I...

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Main Authors: Chun-Shu Wong, Clarisa M. Buckner, Silvia Lucena Lage, Luxin Pei, Felipe L. Assis, Eric W. Dahlstrom, Sarah L. Anzick, Kimmo Virtaneva, Adam Rupert, Jeremy L. Davis, Ting Zhou, Elizabeth Laidlaw, Maura Manion, Frances Galindo, Megan Anderson, Catherine A. Seamon, Michael C. Sneller, Andrea Lisco, Claire Deleage, Stefania Pittaluga, Susan Moir, Irini Sereti
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
HIV
T follicular helper cells
germinal centers
interferon
reconstitution
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/0ae51d691b0641559c9ba2d6466a68a7
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https://doaj.org/article/0ae51d691b0641559c9ba2d6466a68a7

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