VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression

VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression

Recent epidemiological and preclinical evidence indicates that vitamin D3 inhibits colorectal cancer (CRC) progression, but the mechanism has not been completely elucidated. This study was designed to determine the protective effects of vitamin D3 and identify crucial targets and regulatory mechanis...

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Autores principales: Chaojun Zhu, Zihuan Wang, Jianqun Cai, Chunqiu Pan, Simin Lin, Yue Zhang, Yuting Chen, Mengxin Leng, Chengcheng He, Peirong Zhou, Changjie Wu, Yuxin Fang, Qingyuan Li, Aimin Li, Side Liu, Qiuhua Lai
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
colorectal cancer
vitamin D
VDR (vitamin D receptor)
network pharmacology
NAT2 (N-acetyl transferase 2)
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/0aef70055b384406a23076745b5dfbeb
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Internet

https://doaj.org/article/0aef70055b384406a23076745b5dfbeb

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