Modeling somatic and dendritic spike mediated plasticity at the single neuron and network level

Synaptic plasticity is the neuronal mechanism underlying learning. Here the authors construct biophysical models of pyramidal neurons that reproduce observed plasticity gradients along the dendrite and show that dendritic spike dependent LTP which is predominant in distal sections can prolong memory...

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Autores principales: Jacopo Bono, Claudia Clopath
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0af9b233961047b491c6c3764c9c1f42
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