Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glycoconjugates for vaccine development.

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Autores principales: Marielle Tamigney Kenfack, Marcelina Mazur, Teerapat Nualnoi, Teresa L. Shaffer, Abba Ngassimou, Yves Blériot, Jérôme Marrot, Roberta Marchetti, Kitisak Sintiprungrat, Narisara Chantratita, Alba Silipo, Antonio Molinaro, David P. AuCoin, Mary N. Burtnick, Paul J. Brett, Charles Gauthier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0b53724e03a547438b21428813ffebbe
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