Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glycoconjugates for vaccine development.

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Autores principales:	Marielle Tamigney Kenfack, Marcelina Mazur, Teerapat Nualnoi, Teresa L. Shaffer, Abba Ngassimou, Yves Blériot, Jérôme Marrot, Roberta Marchetti, Kitisak Sintiprungrat, Narisara Chantratita, Alba Silipo, Antonio Molinaro, David P. AuCoin, Mary N. Burtnick, Paul J. Brett, Charles Gauthier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0b53724e03a547438b21428813ffebbe
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spelling	oai:doaj.org-article:0b53724e03a547438b21428813ffebbe2021-12-02T13:24:14ZDeciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens10.1038/s41467-017-00173-82041-1723https://doaj.org/article/0b53724e03a547438b21428813ffebbe2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00173-8https://doaj.org/toc/2041-1723Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glycoconjugates for vaccine development.Marielle Tamigney KenfackMarcelina MazurTeerapat NualnoiTeresa L. ShafferAbba NgassimouYves BlériotJérôme MarrotRoberta MarchettiKitisak SintiprungratNarisara ChantratitaAlba SilipoAntonio MolinaroDavid P. AuCoinMary N. BurtnickPaul J. BrettCharles GauthierNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marielle Tamigney Kenfack Marcelina Mazur Teerapat Nualnoi Teresa L. Shaffer Abba Ngassimou Yves Blériot Jérôme Marrot Roberta Marchetti Kitisak Sintiprungrat Narisara Chantratita Alba Silipo Antonio Molinaro David P. AuCoin Mary N. Burtnick Paul J. Brett Charles Gauthier Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
description	Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glycoconjugates for vaccine development.
format	article
author	Marielle Tamigney Kenfack Marcelina Mazur Teerapat Nualnoi Teresa L. Shaffer Abba Ngassimou Yves Blériot Jérôme Marrot Roberta Marchetti Kitisak Sintiprungrat Narisara Chantratita Alba Silipo Antonio Molinaro David P. AuCoin Mary N. Burtnick Paul J. Brett Charles Gauthier
author_facet	Marielle Tamigney Kenfack Marcelina Mazur Teerapat Nualnoi Teresa L. Shaffer Abba Ngassimou Yves Blériot Jérôme Marrot Roberta Marchetti Kitisak Sintiprungrat Narisara Chantratita Alba Silipo Antonio Molinaro David P. AuCoin Mary N. Burtnick Paul J. Brett Charles Gauthier
author_sort	Marielle Tamigney Kenfack
title	Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
title_short	Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
title_full	Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
title_fullStr	Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
title_full_unstemmed	Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
title_sort	deciphering minimal antigenic epitopes associated with burkholderia pseudomallei and burkholderia mallei lipopolysaccharide o-antigens
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0b53724e03a547438b21428813ffebbe
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Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

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